APTO-253

CAT: 0931-T10352-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T10352-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
916151-99-0
Target
KLF|||Apoptosis|||c-Myc
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis|||MAPK
Purity
0.9943
Bioactivity
APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.
Smiles
Cc1[nH]c2ccc(F)cc2c1-c1nc2c([nH]1)c1cccnc1c1ncccc21
Molecular Formula
C22H14FN5
Molecular Weight
367.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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