APTO-253

• Target:

  KLF|||Apoptosis|||c-Myc

• Related Pathways:

  Cell Cycle/Checkpoint|||Apoptosis|||MAPK

• Purity:

  0.9943

• Bioactivity:

  APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.

• Smiles:

  Cc1[nH]c2ccc (F) cc2c1-c1nc2c ([nH]1) c1cccnc1c1ncccc21

• Molecular Formula:

  C22H14FN5

• Molecular Weight:

  367.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  916151-99-0