APTO-253

• Target :

  KLF|||Apoptosis|||c-Myc

• Related Pathways :

  Cell Cycle/Checkpoint|||Apoptosis|||MAPK

• Purity :

  0.9943

• Bioactivity :

  APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.

• Smiles :

  Cc1[nH]c2ccc(F)cc2c1-c1nc2c([nH]1)c1cccnc1c1ncccc21

• Molecular Formula :

  C22H14FN5

• Molecular Weight :

  367.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  916151-99-0