AM-6494

CAT: 0931-T10292-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T10292-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1874232-80-0

Target

Beta-Secretase, BACE

Related Pathways

Neuroscience

Bioactivity

AM-6494, a potent and orally active BACE1 inhibitor (IC50: 0.4 nM), exhibits in vivo selectivity over BACE2 (IC50: 18.6 nM) .

Smiles

C(OC)[C@]12[C@]([C@](C)(N=C(N)S1)C3=CC(NC(=O)C=4C=NC(OCC#C)=CN4)=CC(F)=C3F)(C2)[H]

Molecular Formula

C22H21F2N5O3S

Molecular Weight

473.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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