AM-6494

• Target :

  Beta-Secretase|||BACE

• Related Pathways :

  Neuroscience

• Bioactivity :

  AM-6494, a potent and orally active BACE1 inhibitor (IC50: 0.4 nM), exhibits in vivo selectivity over BACE2 (IC50: 18.6 nM) .

• Smiles :

  C(OC)[C@]12[C@]([C@](C)(N=C(N)S1)C3=CC(NC(=O)C=4C=NC(OCC#C)=CN4)=CC(F)=C3F)(C2)[H]

• Molecular Formula :

  C22H21F2N5O3S

• Molecular Weight :

  473.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1874232-80-0