Oltipraz

CAT: 0931-MF-0003193-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0003193-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
64224-21-1
Target
Nrf2|||Parasite|||Reverse Transcriptase|||HIF/HIF Prolyl-Hydroxylase|||HIV Protease|||HIF
Related Pathways
Proteases/Proteasome|||Immunology/Inflammation|||Chromatin/Epigenetic|||Metabolism|||Microbiology/Virology|||Angiogenesis
Purity
>99.99%
Bioactivity
Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD (P) H: quinone oxidoreductase 1 (NQO1) . The induction of detoxification enzymes enhances the detoxification of certain cancer-causing agents, thereby enhancing their elimination and preventing carcinogen-induced DNA damages. Although the exact mechanism through which the anti-angiogenesis effect remains to be fully elucidated, oltipraz maybe able to modulate the expression of a number of angiogenic factors, thereby blocking the sustained and focal neovascularization in multiple tumor cell types.
Smiles
CC1=C(SSC1=S)C1=NC=CN=C1
Molecular Formula
C8H6N2S3
Molecular Weight
226.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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