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PF-04217903

CAT: 0026-B2062-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2062-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-04217903 is a novel ATP-competitive small-molecule inhibitor of c-Met kinase. PF-04217903 displays more than 1,000-fold selectivity for c-Met compared with more than 150 kinases. PF-04217903 inhibits tumor cell proliferation, survival, migration/invasion in MET-amplified cell lines in vitro and shows marked antitumor activity in tumor models harboring either MET gene amplification or a hepatocyte growth factor (HGF)/c-Met autocrine loop at well-tolerated dose levels in vivo.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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