PF-03814735

CAT: 0026-B1257-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B1257-5Size:5 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-03814735 is an ATP-competitive inhibitor of Aurora kinases A and B with IC₅₀values of 0.8 and 0.5 nM respectively. It has shown to block cytokinesis, inhibit cellular proliferation in many tumor cell lines including HCT-116, HL-60 and A549. In vitro experiments have shown that PF 03814735 inhibits the phosphorylation of Aurora B H3 and Aurora A cultured MDA-MB-231 cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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