PF-670462

CAT: 0026-B2271-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2271-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-670462 is a potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC₅₀ values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other kinases. Inhibits PER protein nuclear translocation (EC₅₀ = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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