PF-573228

CAT: 0026-2819-50Size: 50 mgDry Ice: NoHazardous: No
CAT#:0026-2819-50Size:50 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM.  Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro.
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
36 months