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IGF-1 Antibody

CAT: 0013-GTR18572507Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18572507Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
UniProt
P05019
Reactivity
Human, Mouse, Rat
Immunogen
Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.
Clonality
Monoclonal
Clone
IGF1/1020
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 1-4ug/ml, In-vitro neutralization of biological activity of IGF-1 (order BSA/sodium azide-free format)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the IGF-1 antibody should be determined by the researcher.
Tested Applications
FACS, IF, NeA
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

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