IGF-1 polyclonal antibody

CAT: 0384-BS6817-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS6817-01Size:50 µL
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Background
IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The ; is specific to isoform IGF-1A.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Insulin-like growth factor I; IGF-I; Mechano growth factor; MGF; Somatomedin-C; IGF1; IGF-1; IBP1
Swiss Prot
P05019
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length protein of human IGF1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 8-20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IGF1 polyclonal antibody detects endogenous levels of IGF4 protein.
Applications Notes
Western blot (WB) analysis of IGF-1 pAb at 1:1000 dilution Lane1:The Testis tissue lysate of Mouse (30ug) Lane2:The Testis tissue lysate of Rat (30ug) Lane3:IGF-1 recombinant protein (0.4ug)
Host or Source
Rabbit

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