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LRRK2 Rabbit Polyclonal Antibody (APC)

CAT: 0013-GTR18566869Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18566869Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-LRRK2 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Name Alternative
Leucine-rich repeat serine/threonine-protein kinase 2; 2.7.11.1; Dardarin; LRRK2; PARK8
UniProt
Q5S007
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human LRRK2 recombinant protein (Position: E10-L350) . Human LRRK2 shares 82% amino acid (aa) sequence identity with mouse LRRK2.
Target
Leucine-rich repeat serine/threonine-protein kinase 2
Clonality
Polyclonal
Conjugation
APC
Field of Research
Cell Biology, Neuroscience
Purification
Immunogen affinity purified.
Dilution
Optimal dilutions should be determined by end users.
Form
Liquid
Molecular Weight
286103 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Notes
For research use only.
Applications Notes
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · Q5S007

Leucine-rich repeat serine/threonine-protein kinase 2

LRRK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5S007
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRRK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1, 3.6.5.-
Processing
—
Secondary accessions
A6NJU2, Q6ZS50, Q8NCX9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

ATP-bindingGTP-bindingNucleotide-binding

Biological process

AutophagyDifferentiation

Cellular component

Cell projectionCytoplasmCytoplasmic vesicleCytoskeletonEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembraneMitochondrionMitochondrion outer membraneSynapse

Domain

Coiled coilLeucine-rich repeatRepeatWD repeat

Disease

Disease variantNeurodegenerationParkinson diseaseParkinsonism

Molecular function

GTPase activationHydrolaseKinaseSerine/threonine-protein kinaseTransferase

PTM

PhosphoproteinUbl conjugation

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