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Rabbit Polyclonal Antibody to APC

CAT: 1725-P13143-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P13143-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Product Name Alternative
GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
Swiss Prot
P25054
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human APC
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
APC

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