LS-75

• Description:

  LS-75 is a PARP-1 inhibitor with blood-brain permeability and IC50 value of 18 μM. LS-75 has neuroprotective activity[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PARP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ls-75.html

• Purity:

  99.31

• Smiles:

  O=C1C2=CC=CC=C2NC=3N=CC=CC3N1

• Molecular Formula:

  C12H9N3O

• Molecular Weight:

  211.22

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]André Schrattenholz, et al. Muscarinic antagonists with PARP and SIR modulating activity as agents for inflammatory diseases. US8039464B2.2011-10-18.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [885-70-1]