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EGFR-IN-75

CAT: 0804-HY-152144Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152144Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-75 is an EGFRWT and EGFRT790M inhibitor with IC50 values of 0.28 μM and 5.02 μM, respectively. EGFR-IN-75 shows anticancer and antioxidant activity[1].
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-75.html
Solubility
10 mM in DMSO
Smiles
NC1=NC=NC2=C1SC3=C2C4=C(C(N)=NC=N4)S3
Molecular Formula
C10H6N6S2
Molecular Weight
274.32
References & Citations
[1]Sanaa A Ahmed, et al. Thieno[2,3- b]thiophene Derivatives as Potential EGFRWT and EGFRT790M Inhibitors with Antioxidant Activities: Microwave-Assisted Synthesis and Quantitative In Vitro and In Silico Studies. ACS Omega. 2022 Dec 3;7 (49) :45535-45544.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1