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Falcarinol

CAT: 0804-HY-N1455Size: 1 mg (40.92 mM x 100 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-N1455Size:1 mg (40.92 mM x 100 μL in Ethanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
21852-80-2
Product Name Alternative
Panaxynol; Carotatoxin
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; HSP
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/falcarinol.html
Concentration
40.92 mM * 100 μL in Ethanol
Purity
99.83
Solubility
10 mM in DMSO
Smiles
C=C[C@@H](O)C#CC#CC/C=C\CCCCCCC
Molecular Formula
C17H24O
Molecular Weight
244.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Le HT, et al. Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells. Cancer Lett. 2018 Jan 1;412:297-307.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, protect from light, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported

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