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7-Ethoxyresorufin

CAT: 0804-HY-D0145-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D0145-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2][3][4].
CAS Number
5725-91-7
Product Name Alternative
Resorufin ethyl ether
UNSPSC
12171500
Hazard Statement
H315, H319, H335
Target
Cytochrome P450; NO Synthase
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/7-ethoxyresorufin.html
Purity
99.61
Solubility
DMF : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=CC2=NC3=C(C=C(OCC)C=C3)OC2=C1
Molecular Formula
C14H11NO3
Molecular Weight
241.24
Precautions
H315, H319, H335
References & Citations
[1]C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118 (1) :57-62.|[2]Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90.|[3]Grafstöm R, et al. Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells. Drug Chem Toxicol. 1981;4 (2) :147-59.|[4]Pohl RJ, et al. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Anal Biochem. 1980 Sep 1;107 (1) :150-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
CYP1

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