LY 225910

• Description:

  LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H301, H413

• Target:

  Cholecystokinin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ly-225910.html

• Purity:

  98.92

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1N(C2=CC=CC(OC(C)C)=C2)C(CCC3=CNC4=C3C=C(Br)C=C4)=NC5=C1C=CC=C5

• Molecular Formula:

  C27H24BrN3O2

• Molecular Weight:

  502.40

• Precautions:

  H301, H413

• References & Citations:

  [1]Felicio LF, et al., Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response. Peptides. 2001 Aug;22 (8) :1299-304.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [133040-77-4]