LY 225910

• Description :

  LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H413

• Target :

  Cholecystokinin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ly-225910.html

• Purity :

  98.92

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1N(C2=CC=CC(OC(C)C)=C2)C(CCC3=CNC4=C3C=C(Br)C=C4)=NC5=C1C=CC=C5

• Molecular Formula :

  C27H24BrN3O2

• Molecular Weight :

  502.40

• Precautions :

  H301, H413

• References & Citations :

  [1]Felicio LF, et al., Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response. Peptides. 2001 Aug;22 (8) :1299-304.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [133040-77-4]