LY 225910

• UNSPSC Description:

  LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization[1].

• Target Antigen:

  Cholecystokinin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ly-225910.html

• Smiles:

  O=C1N(C2=CC=CC(OC(C)C)=C2)C(CCC3=CNC4=C3C=C(Br)C=C4)=NC5=C1C=CC=C5

• Molecular Weight:

  502.40

• References & Citations:

  [1]Felicio LF, et al., Stimulation of either cholecystokinin receptor subtype reduces while antagonists potentiate or sensitize a morphine-induced excitatory response. Peptides. 2001 Aug;22(8):1299-304.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  133040-77-4