ADAM17, NT (ADAM17, CSVP, TACE, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b)[ADAM17]
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Catalog numberMBS644197
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PricePlease ask
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SizeNA
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Products_typeAntibody
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ReactivityHuman
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DescriptionThe ADAM17, NT (ADAM17, CSVP, TACE, Disintegrin metalloproteinase domain- protein 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b)[ADAM17] is a α- or alpha protein sometimes glycoprotein present in blood. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNF, ADAM17, TNFRSF1A, TNFRSF1B, LTBR
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Short nameADAM17, NT (ADAM17, CSVP, TACE, Disintegrin metalloproteinase domain- protein 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b)[ADAM17]
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TechniqueEnzyme, enzymes
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HostRabbit
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Alternative nameADAM metallopeptidase domain 17, NT (ADAM metallopeptidase domain 17, CSVP, TACE, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, tumor necrosis factor-a convertase, tumor necrosis factor-a-converting enzyme, CD156b)[ADAM metallopeptidase domain 17]
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Alternative techniqueenzymes
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Alternative to gene targetADAM metallopeptidase domain 17, ADAM18 and CD156B and CSVP and NISBD and TACE, ADAM17 and IDBG-27788 and ENSG00000151694 and 6868, PDZ domain binding, Cell surfaces, Adam17 and IDBG-130508 and ENSMUSG00000052593 and 11491, ADAM17 and IDBG-638333 and ENSBTAG00000001141 and 517541
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Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase domain 17
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor, alpha, converting enzyme
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-04-10
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Entrez gene record
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Pubmed identfication
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Classification
- ADAM metallopeptidase domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID