ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b) Antibody

• Catalog number
  MBS611728
• Price
  Please ask
• Size
  0.25 ml

• Alternative name1
  Anti-ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)
• Alternative name2
  ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)
• Alternative name3
  ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)
• Alternative name4
  ADAM 17, Propeptide Domain
• Alternative name5
  Anti -ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)
• Other names
  ADAM metallopeptidase with thrombospondin type 1 motif, 17, isoform CRA_d; A disintegrin and metalloproteinase with thrombospondin motifs 17; A disintegrin and metalloproteinase with thrombospondin motifs 17; ADAM-TS17; ADAMTS-17; ADAM-TS 17; OTTHUMP00000194818; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17; ADAM metallopeptidase with thrombospondin type 1 motif, 17; N/A
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  ADAMTS17; ADAMTS17; FLJ16363; FLJ32769; N/A
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  N/A
• Clone
  Polyclonal antibody
• Host organism
  Host: Rabbit; Source: Human
• Species reactivity
  Human, Mouse, Rat
• Specificity and cross reactivity
  Recognizes TACE. Species Crossreactivity: Human, Mouse and Rat.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store productone should be stored at -20 degrees Celsius. or colder. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested for
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  The ADAM 17, Propeptide Domain (A Disintegrin Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b) Antibody is a α- or alpha protein sometimes glycoprotein present in blood. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
• Properties
  If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
• French translation
  anticorps

• Gene target
  ADAM   Propeptide   Domain   Disintegrin   Metalloproteinase   TNF-a   Converting   TACE   TNF   alpha   Converting   CD156b  
• Gene symbol
  TNF, TNFRSF1A, TNFRSF1B, LTBR, ADAMTS10, ADAMTS6, ADAMTS8, ADAM17, ADAMTS7, ADAMTS2
• Short name
  ADAM 17, Propeptide Domain (A Disintegrin Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b) Antibody
• Technique
  Antibody, Enzyme, antibodies against human proteins, antibodies for, enzymes
• Alternative name
  ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, tumor necrosis factor-a Converting Enzyme, TACE, tumor necrosis factor a Converting Enzyme, CD156b) (antibody to-)
• Alternative technique
  antibodies, enzymes
• Alternative to gene target
  tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

Gene info

• Identity
  HGNC:13201
• Gene
  ADAMTS10
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 10
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10
• Synonyms
  • ADAM-TS10
• GenBank acession
  • AF163762
• Locus
  19p13.2
• Discovery year
  2001-04-05
• Entrez gene record
  81794
• Pubmed identfication
  • 15355968
  • 15368195
• RefSeq identity
  • NM_030957
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000182216

Gene info

• Identity
  HGNC:222
• Gene
  ADAMTS6
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 6
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6
• Synonyms
  • ADAM-TS6
• Synonyms name
  • a disintegrin and metalloproteinase with thrombospondin motifs 6
• GenBank acession
  • AF140674
• Locus
  5q12.3
• Discovery year
  1999-09-06
• Entrez gene record
  11174
• Pubmed identfication
  • 10464288
• RefSeq identity
  • NM_197941
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000074079

Gene info

• Identity
  HGNC:224
• Gene
  ADAMTS8
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 8
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
• Synonyms
  • METH2
  • FLJ41712
  • ADAM-TS8
• GenBank acession
  • AF060153
• Locus
  11q24.3
• Discovery year
  1999-08-23
• Entrez gene record
  11095
• Pubmed identfication
  • 10438512
• RefSeq identity
  • NM_007037
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000165656

Gene info

• Identity
  HGNC:195
• Gene
  ADAM17
• Long gene name
  ADAM metallopeptidase domain 17
• Synonyms gene
  • TACE
• Synonyms gene name
  • tumor necrosis factor, alpha, converting enzyme
• Synonyms
  • cSVP
  • CD156B
• Synonyms name
  • cartilage snake venom-like protease
  • TNF-alpha convertase enzyme
  • a disintegrin and metalloproteinase 17
• GenBank acession
  • U69611
• Locus
  2p25.1
• Discovery year
  1997-04-10
• Entrez gene record
  6868
• Pubmed identfication
  • 9034190
  • 9574564
• Classification
  • ADAM metallopeptidase domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000090425
• Locus Specific Databases
  • LRG_1203

Gene info

• Identity
  HGNC:223
• Gene
  ADAMTS7
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 7
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
• Synonyms
  • ADAM-TS7
  • DKFZp434H204
• Synonyms name
  • COMPase
  • a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein
• GenBank acession
  • AF140675
• Locus
  15q25.1
• Discovery year
  1999-09-06
• Entrez gene record
  11173
• Pubmed identfication
  • 10464288
• RefSeq identity
  • NM_014272
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000172907

Gene info

• Identity
  HGNC:218
• Gene
  ADAMTS2
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 2
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2
• Synonyms
  • ADAMTS-3
  • hPCPNI
  • PCINP
  • ADAM-TS2
  • NPI
• Synonyms name
  • procollagen I N-proteinase
  • procollagen N-endopeptidase
• GenBank acession
  • AJ003125
• Locus
  5q35.3
• Discovery year
  1999-04-15
• Entrez gene record
  9509
• Pubmed identfication
  • 10094461
  • 15373769
• RefSeq identity
  • NM_014244
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000130915

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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