TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met
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Catalog numberMBS641990
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PricePlease ask
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Size100ug
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Alternative name1Anti-TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met
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Alternative name2TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met
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Alternative name3TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met
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Alternative name4TACE
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Alternative name5Anti -TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met
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Other namestace, isoform A; N/A; CG7908 gene product from transcript CG7908-RB; CG7908-PA; CG7908-PB; Tace-PA; Tace-PB; tace; N/A; N/A
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesTace; N/A; CG7908; CT23908; DmelCG7908; DTACE; TACE; N/A
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismHost: Goat; Source: Human
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Species reactivityHuman
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Specificity and cross reactivityRecognizes human CD156b (C-TERMINAL). Species sequence homology: chicken, hamster and rat.
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Purification methodAffinity Purified by immunoaffinity chromatography.
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Form AppearanceSupplied as a liquid in Tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested forELISA (EL/EIA), Western Blot (WB)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional descriptionThe TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met is a α- or alpha protein sometimes glycoprotein present in blood. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolADAM17, ADAMTS10, ADAMTS6, ADAMTS8, ADAMTS7, TNF, ADAMTS2, TNFRSF1A, TNFRSF1B, LTBR
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Short nameTACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met
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TechniqueEnzyme, enzymes
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Alternative nameTACE, CT (Tumor Necrosis Factor a Converting Enzyme, tumor necrosis factor a Convertase, tumor necrosis factor a Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, a, Converting Enzyme), ADAM 17, ADAM metallopeptidase domain 17, ADAM-17, ADAM metallopeptidase domain 17 Protein, ADAM Met
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Alternative techniqueenzymes
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Alternative to gene targetADAM metallopeptidase domain 17, ADAM18 and CD156B and CSVP and NISBD and TACE, ADAM17 and IDBG-27788 and ENSG00000151694 and 6868, PDZ domain binding, Cell surfaces, Adam17 and IDBG-130508 and ENSMUSG00000052593 and 11491, ADAM17 and IDBG-638333 and ENSBTAG00000001141 and 517541
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase domain 17
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor, alpha, converting enzyme
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-04-10
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Entrez gene record
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Pubmed identfication
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Classification
- ADAM metallopeptidase domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 10
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Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-04-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 6
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Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 8
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Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-08-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 7
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Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 2
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Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-04-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data