ADAM 17, CT (ADAM17, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM Metallopeptidase Domain 17, TNF-alpha Converting Enzyme, A Disintegrin and Met[ADAM 17]
-
Catalog numberMBS659587
-
PricePlease ask
-
SizeNA
-
-
Products_typePeptide
-
DescriptionThe ADAM 17, CT (ADAM17, A Disintegrin Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM Metallopeptidase Domain 17, TNF-alpha Converting Enzyme, A Disintegrin Met[ADAM 17] is a α- or alpha protein sometimes glycoprotein present in blood. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
-
GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
-
Gene target
-
Gene symbolADAM17, TNF, TNFRSF1A, ADAMTS10, ADAMTS6, TNFRSF1B, ADAMTS8, ADAMTS7, ADAMTS2, LTBR
-
Short nameADAM 17, CT (ADAM17, A Disintegrin Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM Metallopeptidase Domain 17, TNF-alpha Converting Enzyme, A Disintegrin Met[ADAM 17]
-
TechniqueEnzyme, enzymes
-
Alternative nameADAM 17, CT (ADAM metallopeptidase domain 17, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, a, Converting Enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM Metallopeptidase Domain 17, tumor necrosis factor-a Converting Enzyme, A Disintegrin and Met[ADAM 17]
-
Alternative techniqueenzymes
-
Alternative to gene targetADAM metallopeptidase domain 17, ADAM18 and CD156B and CSVP and NISBD and TACE, ADAM17 and IDBG-27788 and ENSG00000151694 and 6868, PDZ domain binding, Cell surfaces, Adam17 and IDBG-130508 and ENSMUSG00000052593 and 11491, ADAM17 and IDBG-638333 and ENSBTAG00000001141 and 517541
-
Tissuetumor
-
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase domain 17
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor, alpha, converting enzyme
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1997-04-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- ADAM metallopeptidase domain containing
- CD molecules
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nametumor necrosis factor
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameTNF receptor superfamily member 1A
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-01-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 10
-
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-04-05
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 6
-
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-09-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameTNF receptor superfamily member 1B
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-01-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 8
-
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-08-23
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 7
-
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-09-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 2
-
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-04-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namelymphotoxin beta receptor
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-03-12
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor receptor superfamily
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
-
Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data