Mouse anti Matrix Metalloproteinase 2 (MMP2)

• Catalog number
  X2054M
• Price
  Please ask
• Size
  200 μg

• Category
  Primary Antibodies
• Long description
  The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves Collagen Types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
• Antibody come from
  Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human RYK protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse and rat.
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  4D3
• Antigen antibody binding interaction
  Mouse anti Matrix Metalloproteinase 2 (MMP2) Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  ELISA, Western Blot, Immunohistochemistry
• Antibody s suited for
  Antibody can be used for Western blotting (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. Graham, D.K., et al. (1994). Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. Cell Growth Differ. 5(6):647-657
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Matrix   Metalloproteinase   MMP2  
• Gene symbol
  MMP2-AS1, MMP2
• Short name
  Mouse anti Matrix Metalloproteinase 2 (MMP2)
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to Matrix Metalloproteinase 2 (MMP2)
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:53142
• Gene
  MMP2-AS1
• Long gene name
  MMP2 antisense RNA 1
• Synonyms
  • ENST00000569037
• Locus
  16q12.2
• Discovery year
  2017-02-16
• Entrez gene record
  107984884
• Pubmed identfication
  • 27816668
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:7166
• Gene
  MMP2
• Long gene name
  matrix metallopeptidase 2
• Synonyms gene
  • CLG4
  • CLG4A
• Synonyms gene name
  • matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
• Synonyms
  • TBE-1
• Locus
  16q12.2
• Discovery year
  1989-05-25
• Entrez gene record
  4313
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000133202

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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