Integrin alpha E Antibody

• Catalog number
  R30704
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Integrin alpha E
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Integrin alpha E antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Integrin alpha E antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P38570
• Purity
  Antigen affinity
• Description
  ITGAE (Integrin alpha E), also known as CD103, is a protein that in human is encoded by the ITGAE gene. ITGAE is expressed widely on intraepithelial lymphocyte (IEL) T cells (both alphabeta T cells and gammadelta T cells) and on some peripheral regulatory T cells (Tregs), which is important for decreasing the immune response and appears to play a crucial role in the prevention of autoimmune diseases. ITGAE shares overall homology with other alpha integrins but has a unique 55-amino acid extra region located just N-terminal to the I domain that contains 18 consecutive charged residues and a proteolytic cleavage site.
• Immunogen
  An amino acid sequence from the C-terminus of human Integrin alpha E (KRKYQQLNLESIRKAQ) was used as the immunogen for this Integrin alpha E antibody.
• Storage
  After reconstitution, the Integrin alpha E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Additional description
  The Anti-Integrin alpha E is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Integrin   alpha  
• Gene symbol
  ITGAE
• Short name
  Anti-Integrin alpha E
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Integrin alpha E
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6147
• Gene
  ITGAE
• Long gene name
  integrin subunit alpha E
• Synonyms gene name
  • integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
• Synonyms
  • CD103
  • HUMINAE
• Synonyms name
  • antigen CD103
  • human mucosal lymphocyte antigen 1, alpha polypeptide
• GenBank acession
  • L25851
• Locus
  17p13.2
• Discovery year
  1997-06-09
• Entrez gene record
  3682
• Pubmed identfication
  • 8119947
• RefSeq identity
  • NM_002208
• Classification
  • CD molecules
  • Integrin alpha subunits
• VEGA ID
  OTTHUMG00000177634

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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