Integrin alpha 2/CD49b Antibody
-
Catalog number
bs-10132R
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
Integrin alpha 2/CD49b Antibody
-
Also known as
Integrin alpha 2/CD49b Antibody
-
Category
Primary Antibodies
-
Conjugation
Unconjugated
-
Target Antigen
Integrin alpha 2/CD49b
-
Specificity
This is a highly specific antibody against Integrin alpha 2/CD49b.
-
Modification s
None
-
Modification site s
Unmodified antibody
-
Clonality
Polyclonal antibody
-
Clone number
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Subcellular location
Extracellular, Secreted
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin alpha 2/CD49b
-
Tested Applications
WB, FCM, IHC-P, IF(IHC-P)
-
Recommended dilutions
WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivity
Human
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigen
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym names
Integrin alpha 2; CD49b antigen; BR; CD 49b; CD49 antigen like family member B; CD49b; CD49b; Collagen receptor; DX5 ; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency, included; GPIa; HPA 5 included; HPA5 included; Itga2; Platelet alloantigen Bra, included; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/Iia; Platelet membrane glycoprotein Ia; Platelet receptor for collagen, deficiency of, included; Very late activation protein 2 receptor alpha 2 subunit; VLA 2 alpha chain; VLA 2; VLA 2 subunit alpha; VLA2 alpha chain; ITA2_HUMAN.
-
Description
The Anti-Integrin alpha 2/CD49b is a α- or alpha protein sometimes glycoprotein present in blood.
-
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
ITGA2
-
Short name
Anti-Integrin alpha 2/CD49b
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Host
Rabbit (Oryctolagus cuniculus)
-
Isotype
Immunoglobulin G (IgG)
-
Alternative name
Integrin alpha 2/CD49b Antibody
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
integrin subunit alpha 2
-
Synonyms gene
-
Synonyms gene name
- integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
1991-08-06
-
Entrez gene record
-
RefSeq identity
-
Classification
- Integrin alpha subunits
- CD molecules
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
