Integrin alpha 3 Antibody

• Catalog number
  R30702
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Integrin alpha 3
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Integrin alpha 3 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P26006
• Purity
  Antigen affinity
• Description
  ITGA3 (Integrin alpha 3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. It is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of the human protein increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, two potential cleavage sites, and the the N-terminal repeating units characteristic of ITGAs.
• Immunogen
  An amino acid sequence from the N-terminus of human ITG3A (LFGYSVALHRQTERQQR) was used as the immunogen for this Integrin alpha 3 antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Additional description
  The Anti-Integrin alpha 3 is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Integrin   alpha  
• Gene symbol
  ITGAM, ITGAX, ITGA3
• Short name
  Anti-Integrin alpha 3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Integrin alpha 3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6149
• Gene
  ITGAM
• Long gene name
  integrin subunit alpha M
• Synonyms gene
  • CR3A
  • CD11B
• Synonyms gene name
  • integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
  • integrin, alpha M (complement component 3 receptor 3 subunit)
• Synonyms
  • MAC-1
  • CD11b
• Synonyms name
  • complement component 3 receptor 3 subunit
  • macrophage-1 antigen alpha subunit
• GenBank acession
  • J03925
• Locus
  16p11.2
• Discovery year
  1988-08-05
• Entrez gene record
  3684
• RefSeq identity
  • NM_000632
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000176612
• Locus Specific Databases
  • LRG_1333

Gene info

• Identity
  HGNC:6152
• Gene
  ITGAX
• Long gene name
  integrin subunit alpha X
• Synonyms gene
  • CD11C
• Synonyms gene name
  • integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
  • integrin, alpha X (complement component 3 receptor 4 subunit)
• Synonyms
  • CD11c
• Synonyms name
  • complement component 3 receptor 4 subunit
• GenBank acession
  • BC038237
• Locus
  16p11.2
• Discovery year
  1988-08-15
• Entrez gene record
  3687
• Pubmed identfication
  • 3284962
  • 2303426
• RefSeq identity
  • NM_000887
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000132465

Gene info

• Identity
  HGNC:6139
• Gene
  ITGA3
• Long gene name
  integrin subunit alpha 3
• Synonyms gene
  • MSK18
• Synonyms gene name
  • antigen identified by monoclonal antibody J143
  • integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
• Synonyms
  • CD49c
  • VLA3a
  • VCA-2
  • GAP-B3
• Synonyms name
  • alpha 3 subunit of VLA-3 receptor
  • antigen CD49C
• GenBank acession
  • M59911
• Locus
  17q21.33
• Discovery year
  1992-02-27
• Entrez gene record
  3675
• Pubmed identfication
  • 1655803
  • 9704023
• RefSeq identity
  • NM_005501
• Classification
  • Integrin alpha subunits
  • CD molecules
• VEGA ID
  OTTHUMG00000161890

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products