Mouse Monoclonal [clone EM-20] (IgG2a) to Human PRNP / PrP / Prion

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

Monoclonal EM-20] IgG2a PRNP PrP Prion
Gene symbol

PIRC103, SNORD114-20, SNORD116-20, IGLVI-20, PIRC104, IGHV3-20, SNORD115-20
Short name

Mouse Monoclonal [clone EM-20] (IgG2a) PRNP / PrP / Prion
Technique

Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
Host

mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
Isotype

IgG2a
Species

Human, Humans, Mouses
Alternative name

Mouse monoclonal [clonality EM-20] (IgG2a) to H. sapiens prion protein / PrP / Prion
Alternative technique

murine
Alternative to gene target

prion protein, AltPrP and ASCR and CD230 and CJD and GSS and KURU and p27-30 and PRIP and PrP and PrP27-30 and PrP33-35C and PrPc, PRNP and IDBG-49833 and ENSG00000171867 and 5621, chaperone binding, nuclei, Prnp and IDBG-260830 and ENSMUSG00000079037 and 19122, PRNP and IDBG-639760 and ENSBTAG00000027937 and 281427
Clone name

EM-20

Identity

HGNC:5934
Gene

IGLVI-20
Long gene name

immunoglobulin lambda variable (I)-20 (pseudogene)
Synonyms gene name
- immunoglobulin lambda variable (I)-20
- immunoglobulin lambda variable (I)-20 pseudogene
Synonyms
- IGLV(I)-20
GenBank acession
- D87007
Locus

22q11.22
Discovery year

2000-05-08
Entrez gene record

28769
RefSeq identity
- NG_000002
Classification
- Immunoglobulin lambda locus at 22q11.2
VEGA ID

OTTHUMG00000151242