Human Cleaved CASP8 (Cleaved Caspase-8)[Cleaved CASP8 (Cleaved Caspase-8)]

• Catalog number
  MBS766157
• Price
  Please ask
• Size
  5x96-Strip-Wells

• Products_type
  ELISA Kit
• Products_gene_name
  [CASP8]
• Reactivity
  Human
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Cleaved   CASP8   Cleaved   Caspase-8   [Cleaved   CASP8   Cleaved   Caspase-8  
• Gene symbol
  CASP8
• Short name
  Cleaved CASP8 (Cleaved Caspase-8)[Cleaved CASP8 (Cleaved Caspase-8)]
• Species
  Human, Humans
• Alternative name
  H. sapiens Cleaved caspase 8, apoptosis-related cysteine peptidase (Cleaved caspase-8)[Cleaved caspase 8, apoptosis-related cysteine peptidase (Cleaved caspase-8)]
• Alternative to gene target
  caspase 8, apoptosis-related cysteine peptidase, ALPS2B and CAP4 and Casp-8 and FLICE and MACH and MCH5, CASP8 and IDBG-78534 and ENSG00000064012 and 841, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, nuclei, Casp8 and IDBG-157464 and ENSMUSG00000026029 and 12370, CASP8 and IDBG-643207 and ENSBTAG00000015718 and 507481

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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