Caspase 3, Cleaved (Asp175) (CPP-32, Apoptain, Yama, SCA-1)

Products_type

Antibody
Products_short_name

[Caspase 3, Cleaved]
Products_name_syn

[Anti -Caspase 3, Cleaved (Asp175) (CPP-32, Apoptain, Yama, SCA-1)]
Other_names

[caspase 3]
Clonality

Monoclonal
Clone

[9j115]
Reactivity

Human, Monkey, Mouse, Rat
Specificity

Recognizes endogenous levels of the large fragment (17/19kD) of activated human Caspase 3 resulting from cleavage adjacent to Asp175. Does not recognize full length Caspase 3 or other cleaved caspases. Species Crossreactivity
Purity

Supernatant Supernatant
Form

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA,
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested_application

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Gene target

Caspase Cleaved Asp175 CPP-32 Apoptain Yama SCA-1
Gene symbol

CPP, LY6E, MILR1, IGKV1D-32, SNORD115-32, ATXN1, PPP1R1B, IGHV3-32, IGKV1-32, IGLV3-32
Short name

Caspase 3, Cleaved (Asp175) (CPP-32, Apoptain, Yama, SCA-1)
Host

Rabbit
Isotype

IgG
Alternative name

caspase 3, Cleaved (Asp175) (CPP-32, Apoptain, Yama, SCA-1)

Identity

HGNC:27570
Gene

MILR1
Long gene name

mast cell immunoglobulin like receptor 1
Synonyms gene
- C17orf60
Synonyms gene name
- chromosome 17 open reading frame 60
- mast cell immunoglobulin-like receptor 1
Synonyms
- Allergin-1
- MCA-32
Synonyms name
- allergy inhibitory receptor 1
- mast cell antigen 32
GenBank acession
- BC053534
Locus

17q23.3
Discovery year

2005-12-16
Entrez gene record

284021
Pubmed identfication
- 20526344
RefSeq identity
- NM_001085423
Classification
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000185198

Identity

HGNC:10548
Gene

ATXN1
Long gene name

ataxin 1
Synonyms gene
- SCA1
Synonyms gene name
- spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1)
Synonyms
- D6S504E
- ATX1
GenBank acession
- X79204
Locus

6p22.3
Discovery year

1986-01-01
Entrez gene record

6310
Pubmed identfication
- 1582256
RefSeq identity
- NM_000332
Classification
- Ataxins
VEGA ID

OTTHUMG00000014303
Locus Specific Databases
- LRG_863

Identity

HGNC:5595
Gene

IGHV3-32
Long gene name

immunoglobulin heavy variable 3-32 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable 3-32
- immunoglobulin heavy variable 3-32 pseudogene
GenBank acession
- M99664
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28435
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152063

Identity

HGNC:5736
Gene

IGKV1-32
Long gene name

immunoglobulin kappa variable 1-32 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 1-32
- immunoglobulin kappa variable 1-32 pseudogene
GenBank acession
- X71883
Locus

2p11.2
Discovery year

2000-04-18
Entrez gene record

28934
RefSeq identity
- NG_000834
Classification
- Immunoglobulin kappa locus at 2p11.2
VEGA ID

OTTHUMG00000151687

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495