Human Cleaved CASP8 (Cleaved Caspase-8)
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Catalog number
MBS766157
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Price
Please ask
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Size
10x96-Strip-Wells
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Products_type
ELISA Kit
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Products_short_name
[Cleaved CASP8 (Cleaved Caspase-8)]
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Other_names
[CASP8 and FADD-like apoptosis regulator isoform 1; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD like apoptosis regulator; Caspase homolog; CASH]
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Products_gene_name
[CASP8]
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Other_gene_names
[CFLAR; CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1; CASH; CASP8AP1; CLARP; MRIT; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT]
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Reactivity
Human
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Specificity
This assay has high sensitivity and excellent specificity for detection of Cleaved CASP8 . No significant cross-reactivity or interference between Cleaved CASP8 and analogues was observed.
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Storage_stability
4 degree C for 6 months
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Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbol
CASP8
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Short name
Cleaved CASP8 (Cleaved Caspase-8)
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Species
Human, Humans
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Alternative name
H. sapiens Cleaved caspase 8, apoptosis-related cysteine peptidase (Cleaved caspase-8)
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Alternative to gene target
caspase 8, apoptosis-related cysteine peptidase, ALPS2B and CAP4 and Casp-8 and FLICE and MACH and MCH5, CASP8 and IDBG-78534 and ENSG00000064012 and 841, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, nuclei, Casp8 and IDBG-157464 and ENSMUSG00000026029 and 12370, CASP8 and IDBG-643207 and ENSBTAG00000015718 and 507481
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Gene info
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Identity
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Gene
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Long gene name
caspase 8
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Synonyms gene name
- caspase 8, apoptosis-related cysteine protease
- caspase 8, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
Product images
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