Cleaved Caspase 3 antibody

Type

primary antibody
Shipping

Ice bag
Antigen

Cleaved Caspase 3 antibody
Reactivity

Human,Mouse,Rat
Clonality

Monoclonal
Application

WB,IHC
Application_advice

WB(1:500-1:2000), IHC(1:200-1:1000)
Immunogen

Purified recombinant fragment of human Caspase 3 expressed in E. Coli.
Purification

Affinity-chromatography.
Format

Liquid
Concentration

1mg/ml
Fragment

Fab fragment
Storage_Buffer

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Specificity

Caspase 3 (p17,Cleaved-Asp175) Antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.
GendID

836
Gene

CASP3
GeneAlias

CASP3 CPP32
Unigene

Hs.141125;
Swiss Prot

P42574
Weight

17kDa
Datasheet
Msds
Properties

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
French translation

anticorps

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495