BACE1, Ectodomain (Beta-site APP Cleaving Enzyme)
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Catalog numberMBS603084
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PricePlease ask
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Size5x0.5 mg
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Products_typeAntibody
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Products_short_name[BACE1, Ectodomain]
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Products_name_syn[Anti -BACE1, Ectodomain (Beta-site APP Cleaving Enzyme)]
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Other_names[beta-secretase 1 isoform 2; Beta-secretase 1; beta-secretase 1; ASP2; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; membrane-associated aspartic protease 2; beta-site amyloid precursor protein cleaving enzyme 1; beta-site APP cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]
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Other_gene_names[Bace1; Bace1; C76936; Bace; ASP2; Asp 2]
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ClonalityMonoclonal
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Clone[8H105]
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ReactivityHuman, Mouse
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SpecificityRecognizes human BACE1. Species Crossreactivity: mouse.
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
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Storage_stabilityLyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionEnzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbolAPP-DT, BACE1, BACE1-AS, APP, PABPC4, NAE1
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Short nameBACE1, Ectodomain (Beta-site APP Cleaving Enzyme)
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TechniqueEnzyme, enzymes
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HostMouse
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IsotypeIgG1
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Alternative nameBACE1, Ectodomain (b-site amyloid beta (A4) precursor protein Cleaving Enzyme)
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Alternative techniqueenzymes
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Alternative to gene targetamyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene nameAPP divergent transcript
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Locus
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Discovery year2020-06-12
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namebeta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
- Peptidase family A1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBACE1 antisense RNA
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Synonyms gene
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Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year2009-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameamyloid beta precursor protein
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Synonyms gene
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Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepoly(A) binding protein cytoplasmic 4
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Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNEDD8 activating enzyme E1 subunit 1
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Synonyms gene
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Synonyms gene name
- amyloid beta precursor protein binding protein 1, 59kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ubiquitin like modifier activating enzymes
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VEGA ID