- Catalog numberE-CL-H0190-96T
- Product nameHuman BACE1 (Beta-site APP Cleaving Enzyme 1) CLIA Kit
- Size96Test
- PriceAsk For Price
- Detection TypeColormetric
- Target SpeciesHuman
- Target SynonymASP2, HSPC104, Beta Secretase 1, Memapsin 2, membrane-associated aspartic protease 2, aspartyl protease 2
- Test principleThis CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human BACE1 . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human BACE1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human BACE1 , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Human BACE1 . You can calculate the concentration of Human BACE1 in the samples by comparing the RLU value of the samples to the standard curve.
- Sensitivity0.09ng/mL
- Detection Range0.16~10ng/mL
- Target NameBACE1
- UNIProt IDNA
- Tested Sample TypesSerum, Plasma, Cell supernatant
- Product NameHuman BACE1 (Beta-site APP Cleaving Enzyme 1) CLIA Kit
- TypeSandwich
- Technical data
- Standard Curve RUL
- Alternative to gene target
- [ "amyloid beta (A4) precursor protein", "AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2", "APP and IDBG-1100 and ENSG00000142192 and 351", "growth factor receptor binding", "nuclei", "App and IDBG-172954 and ENSMUSG00000022892 and 11820", "APP and IDBG-630293 and ENSBTAG00000017753 and 280722" ]
- [ "v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog", "C-Kit and CD117 and PBT and SCFR", "KIT and IDBG-18980 and ENSG00000157404 and 3815", "transferase activity", "Extracellular", "Kit and IDBG-172083 and ENSMUSG00000005672 and 16590", "KIT and IDBG-642326 and ENSBTAG00000002699 and 280832" ]
- Gene targetBACE1 Beta-site APP Cleaving 1 CLIA Kit
- Identity:HGNC:55075
- Gene:APP-DT
- Long gene name:APP divergent transcript
- Discovery year:2020-06-12
- Classification:Divergent transcripts
- Identity:HGNC:933
- Gene:BACE1
- Long gene name:beta-secretase 1
- Synonyms gene name:beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1
- Discovery year:1999-10-29
- Entrez gene record:23621
- Pubmed identification:10531052
- Classification:Peptidase family A1
- VEGA ID:OTTHUMG00000160636
- Identity:HGNC:37125
- Gene:BACE1-AS
- Long gene name:BACE1 antisense RNA
- Synonyms gene name:BACE1 antisense RNA (non-protein coding)
- Synonyms:FJ573250NCRNA00177BACE1-AS1
- Discovery year:2009-07-15
- Entrez gene record:100379571
- Pubmed identification:18587408, 21785702
- RefSeq identity:NR_037803
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000188154
- Identity:HGNC:620
- Gene:APP
- Long gene name:amyloid beta precursor protein
- Synonyms gene name:Alzheimer disease, amyloid beta (A4) precursor protein
- Synonyms:alpha-sAPP,
- Discovery year:1986-01-01
- Entrez gene record:351
- Pubmed identification:1679289
- RefSeq identity:NM_000484
- Classification:Receptor ligands
- VEGA ID:OTTHUMG00000078438
- Identity:HGNC:8557
- Gene:PABPC4
- Long gene name:poly(A) binding protein cytoplasmic 4
- Synonyms gene name:poly(A)-binding protein, cytoplasmic 4 (inducible form), poly(A) binding protein, cytoplasmic 4 (inducible form)
- Synonyms:iPABP, APP-1
- Discovery year:1999-12-17
- Entrez gene record:8761
- Pubmed identification:10543404
- RefSeq identity:NM_001135653
- Classification:RNA binding motif containing, Small nucleolar RNA protein coding host genes
- VEGA ID:OTTHUMG00000009097
- Identity:HGNC:621
- Gene:NAE1
- Long gene name:NEDD8 activating enzyme E1 subunit 1
- Synonyms gene name:amyloid beta precursor protein binding protein 1, 59kDa
- Synonyms:ula-1APP-BP1
- Discovery year:1999-01-13
- Entrez gene record:8883
- Pubmed identification:8626687, 12740388
- RefSeq identity:NM_003905
- Classification:Ubiquitin like modifier activating enzymes
- VEGA ID:OTTHUMG00000137513
- Gene symbolAPP-DT, BACE1, BACE1-AS, APP, PABPC4, NAE1
- Short nameBACE1 (Beta-site APP Cleaving Enzyme 1) CLIA Kit
- technique filter
- Enzyme
- TechniqueEnzyme, enzymes
- Alternative techniqueenzymes, kits
Gene info
Gene info
Gene info
Gene info
Locus Specific Databases:Alzheimer Disease & Frontotemporal Dementia Mutation Database