- Catalog numberGEN633019
- Product nameBACE, Asp2 (Beta-secretase 1, Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE1, KIAA1149) Antibody
- Size100ug
- PriceAsk For Price
- Also known asBACE, Asp2
- Other namesbeta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
- CategoryAntibodies
- SubcategoryMnoclonal antibodies
- Gene nameBACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2
- Gene name synonimsBACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2
- Other gene namesBACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2
- ClonalityMonoclonal
- Immunoglobulin isotypeIgG1
- Clone11C83
- Host organismMouse (Mus musculus)
- Source organismHuman (Homo sapiens)
- Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
- Specificity and cross reactivityRecognizes human BACE, asp2.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
- Purification methodAffinity Purified by immunoaffinity chromatography.
- Form AppearanceSupplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
- ConcentrationN/A
- Storage and shippingLyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Tested applicationsELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
- Alternative to gene target
- [ "amyloid beta (A4) precursor protein", "AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2", "APP and IDBG-1100 and ENSG00000142192 and 351", "growth factor receptor binding", "nuclei", "App and IDBG-172954 and ENSMUSG00000022892 and 11820", "APP and IDBG-630293 and ENSBTAG00000017753 and 280722" ]
- Gene targetBACE Asp2 Beta-secretase 1 Aspartyl Protease 2 ASP2 Asp 2 Beta-site Amyloid Precursor Protein Cleaving 1 Beta-site APP Cleaving 1 Memapsin-2 Membrane-associated Aspartic Protease 2 BACE1 KIAA1149
- Identity:HGNC:933
- Gene:BACE1
- Long gene name:beta-secretase 1
- Synonyms gene name:beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1
- Discovery year:1999-10-29
- Entrez gene record:23621
- Pubmed identification:10531052
- Classification:Peptidase family A1
- VEGA ID:OTTHUMG00000160636
- Identity:HGNC:55075
- Gene:APP-DT
- Long gene name:APP divergent transcript
- Discovery year:2020-06-12
- Classification:Divergent transcripts
- Identity:HGNC:37125
- Gene:BACE1-AS
- Long gene name:BACE1 antisense RNA
- Synonyms gene name:BACE1 antisense RNA (non-protein coding)
- Synonyms:FJ573250NCRNA00177BACE1-AS1
- Discovery year:2009-07-15
- Entrez gene record:100379571
- Pubmed identification:18587408, 21785702
- RefSeq identity:NR_037803
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000188154
- Identity:HGNC:620
- Gene:APP
- Long gene name:amyloid beta precursor protein
- Synonyms gene name:Alzheimer disease, amyloid beta (A4) precursor protein
- Synonyms:alpha-sAPP,
- Discovery year:1986-01-01
- Entrez gene record:351
- Pubmed identification:1679289
- RefSeq identity:NM_000484
- Classification:Receptor ligands
- VEGA ID:OTTHUMG00000078438
- Identity:HGNC:8557
- Gene:PABPC4
- Long gene name:poly(A) binding protein cytoplasmic 4
- Synonyms gene name:poly(A)-binding protein, cytoplasmic 4 (inducible form), poly(A) binding protein, cytoplasmic 4 (inducible form)
- Synonyms:iPABP, APP-1
- Discovery year:1999-12-17
- Entrez gene record:8761
- Pubmed identification:10543404
- RefSeq identity:NM_001135653
- Classification:RNA binding motif containing, Small nucleolar RNA protein coding host genes
- VEGA ID:OTTHUMG00000009097
- Identity:HGNC:621
- Gene:NAE1
- Long gene name:NEDD8 activating enzyme E1 subunit 1
- Synonyms gene name:amyloid beta precursor protein binding protein 1, 59kDa
- Synonyms:ula-1APP-BP1
- Discovery year:1999-01-13
- Entrez gene record:8883
- Pubmed identification:8626687, 12740388
- RefSeq identity:NM_003905
- Classification:Ubiquitin like modifier activating enzymes
- VEGA ID:OTTHUMG00000137513
- Gene symbolBACE1, APP-DT, BACE1-AS, APP, PABPC4, NAE1
- Short nameBACE, Asp2 (Beta-secretase 1, Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, -associated Aspartic Protease 2, BACE1, KIAA1149) Antibody
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- Antibody
- Enzyme
- TechniqueAntibody, Enzyme, antibodies against human proteins, antibodies for, enzymes
- Alternative techniqueantibodies, enzymes
Gene info
Gene info
Gene info
Gene info
Locus Specific Databases:Alzheimer Disease & Frontotemporal Dementia Mutation Database