Activin Receptor Type IIA (RIIA) (Biotin)

• Catalog number
  MBS622684
• Price
  Please ask
• Size
  5x0.05 mg

• Products_type
  Antibody
• Products_short_name
  [Activin Receptor Type IIA]
• Products_name_syn
  [Anti -Activin Receptor Type IIA (RIIA) (Biotin)]
• Other_names
  [activin receptor type-2A; Activin receptor type-2A; activin receptor type-2A; ACTR-IIA; activin receptor IIA; type II activin receptor; activin receptor type IIA; activin A receptor, type IIA; Activin receptor type IIA]
• Other_gene_names
  [Acvr2a; Acvr2a; Acvr2; rActR-II; Actrii; Acvr2]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human Activin RIIA extracellular domain.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS. Reconstitute with 40-50% glycerol, PBS.
• Storage_stability
  Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB)
• Properties
  Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Conjugation
  Biotinylated
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Activin   Receptor   IIA   RIIA  
• Gene symbol
  MYH2, FCGR2A
• Short name
  Activin Receptor IIA (RIIA) ( )
• Host
  Goat
• Isotype
  IgG
• Label
  Biotin
• Alternative name
  Activin Receptor classification IIA (RIIA) (biotinilated)

Gene info

• Identity
  HGNC:7572
• Gene
  MYH2
• Long gene name
  myosin heavy chain 2
• Synonyms gene
  • IBM3
• Synonyms gene name
  • myosin, heavy polypeptide 2, skeletal muscle, adult
  • inclusion body myopathy 3, autosomal dominant
• Synonyms
  • MYH2A
  • MYHSA2
  • MyHC-IIa
  • MYHas8
  • MyHC-2A
• Locus
  17p13.1
• Discovery year
  2001-06-22
• Entrez gene record
  4620
• Pubmed identfication
  • 7545970
  • 11889243
• RefSeq identity
  • NM_017534
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000130363

Gene info

• Identity
  HGNC:3616
• Gene
  FCGR2A
• Long gene name
  Fc gamma receptor IIa
• Synonyms gene
  • FCG2
  • FCGR2A1
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG receptor IIa
• Synonyms
  • CD32
  • CD32A
  • IGFR2
  • CDw32
  • Fc-gamma-RIIa
  • FcgammaRIIa
• Synonyms name
  • Immunoglobulin G Fc receptor II
• GenBank acession
  • J03619
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2212
• Pubmed identfication
  • 2139735
  • 8994865
• RefSeq identity
  • NM_021642
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034469
• Locus Specific Databases
  • LRG_1109

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