Activin Receptor Type IIA (RIIA) (Biotin)
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Catalog numberMBS622684
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Price:
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Size5x0.05 mg
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Products_typeAntibody
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Products_short_name[Activin Receptor Type IIA]
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Products_name_syn[Anti -Activin Receptor Type IIA (RIIA) (Biotin)]
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Other_names[activin receptor type-2A; Activin receptor type-2A; activin receptor type-2A; ACTR-IIA; activin receptor IIA; type II activin receptor; activin receptor type IIA; activin A receptor, type IIA; Activin receptor type IIA]
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Other_gene_names[Acvr2a; Acvr2a; Acvr2; rActR-II; Actrii; Acvr2]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificityRecognizes human Activin RIIA extracellular domain.
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PurityAffinity Purified Purified by immunoaffinity chromatography.
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FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS. Reconstitute with 40-50% glycerol, PBS.
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Storage_stabilityLyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB)
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PropertiesBiotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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ConjugationBiotinylated
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolMYH2, FCGR2A
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Short nameActivin Receptor IIA (RIIA) ( )
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HostGoat
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IsotypeIgG
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LabelBiotin
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Alternative nameActivin Receptor classification IIA (RIIA) (biotinilated)
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Gene info
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Identity
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Gene
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Long gene namemyosin heavy chain 2
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Synonyms gene
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Synonyms gene name
- myosin, heavy polypeptide 2, skeletal muscle, adult
- inclusion body myopathy 3, autosomal dominant
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myosin heavy chains, class II
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFc gamma receptor IIa
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgG, low affinity IIa, receptor for (CD32)
- Fc fragment of IgG, low affinity IIa, receptor (CD32)
- Fc fragment of IgG receptor IIa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-11-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases