Activin Receptor Type IIA (RIIA)
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Catalog numberGEN606695
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Price:
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Size500ug
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Also known asActivin Receptor Type IIA
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Other namesactivin receptor type-2A; Activin receptor type-2A; activin receptor type-2A; ACTR-IIA; activin receptor IIA; type II activin receptor; activin receptor type IIA; activin A receptor, type IIA; Activin receptor type IIA
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameAcvr2a; Acvr2a; Acvr2; rActR-II; Actrii; Acvr2
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Gene name synonimsAcvr2a; Acvr2a; Acvr2; rActR-II; Actrii; Acvr2
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Other gene namesAcvr2a; Acvr2a; Acvr2; rActR-II; Actrii; Acvr2
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2a
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Clone9H20
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human Activin RIIA. Does not crossreact with recombinant human Activin RIA, recombinant human Activin RIB or recombinant human Activin RIIB.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein A affinity chromatography.
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Form AppearanceSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
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ConcentrationN/A
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Storage and shippingLyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolMYH2, FCGR2A
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Short nameActivin Receptor IIA (RIIA)
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Alternative nameAnti-Activin Receptor Type IIA (RIIA)
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Gene info
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Identity
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Gene
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Long gene namemyosin heavy chain 2
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Synonyms gene
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Synonyms gene name
- myosin, heavy polypeptide 2, skeletal muscle, adult
- inclusion body myopathy 3, autosomal dominant
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myosin heavy chains, class II
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFc gamma receptor IIa
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgG, low affinity IIa, receptor for (CD32)
- Fc fragment of IgG, low affinity IIa, receptor (CD32)
- Fc fragment of IgG receptor IIa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-11-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases