Activin Receptor Type IIA (RIIA)

• Catalog number
  MBS606695
• Price
  Please ask
• Size
  0.5 mg

• Products_type
  Antibody
• Products_short_name
  [Activin Receptor Type IIA]
• Products_name_syn
  [Anti -Activin Receptor Type IIA (RIIA)]
• Other_names
  [activin receptor type-2A; Activin receptor type-2A; activin receptor type-2A; ACTR-IIA; activin receptor IIA; type II activin receptor; activin receptor type IIA; activin A receptor, type IIA; Activin receptor type IIA]
• Other_gene_names
  [Acvr2a; Acvr2a; Acvr2; rActR-II; Actrii; Acvr2]
• Clonality
  Monoclonal
• Clone
  [9H20]
• Reactivity
  Human
• Specificity
  Recognizes human Activin RIIA. Does not crossreact with recombinant human Activin RIA, recombinant human Activin RIB or recombinant human Activin RIIB.
• Purity
  Purified by Protein A affinity chromatography from hybridoma culture supernatant.
• Form
  Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 1ml sterile PBS.
• Concentration
  ~0.5mg/ml (after reconsitution)
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Activin   Receptor   IIA   RIIA  
• Gene symbol
  MYH2, FCGR2A
• Short name
  Activin Receptor IIA (RIIA)
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  Activin Receptor classification IIA (RIIA)

Gene info

• Identity
  HGNC:7572
• Gene
  MYH2
• Long gene name
  myosin heavy chain 2
• Synonyms gene
  • IBM3
• Synonyms gene name
  • myosin, heavy polypeptide 2, skeletal muscle, adult
  • inclusion body myopathy 3, autosomal dominant
• Synonyms
  • MYH2A
  • MYHSA2
  • MyHC-IIa
  • MYHas8
  • MyHC-2A
• Locus
  17p13.1
• Discovery year
  2001-06-22
• Entrez gene record
  4620
• Pubmed identfication
  • 7545970
  • 11889243
• RefSeq identity
  • NM_017534
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000130363

Gene info

• Identity
  HGNC:3616
• Gene
  FCGR2A
• Long gene name
  Fc gamma receptor IIa
• Synonyms gene
  • FCG2
  • FCGR2A1
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG receptor IIa
• Synonyms
  • CD32
  • CD32A
  • IGFR2
  • CDw32
  • Fc-gamma-RIIa
  • FcgammaRIIa
• Synonyms name
  • Immunoglobulin G Fc receptor II
• GenBank acession
  • J03619
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2212
• Pubmed identfication
  • 2139735
  • 8994865
• RefSeq identity
  • NM_021642
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034469
• Locus Specific Databases
  • LRG_1109

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