Activin Receptor Type IIA (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2) (APC)

• Catalog number
  MBS6002407
• Price
  Please ask
• Size
  100 Tests

• Other size
  please contact us to order other different size
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Activin   Receptor   IIA   Activin   Receptor   Activin   Receptor   IIA   ACTR-IIA   ACTRIIA   ACVR2A   ACVR2   APC  
• Gene symbol
  MYH2, ACVR2A, ACVR2B, APC, NCOA3
• Short name
  Activin Receptor IIA (Activin Receptor -2A, Activin Receptor IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2) (APC)
• Label
  APC
• Alternative name
  Activin Receptor classification IIA (Activin Receptor classification-2A, Activin Receptor classification IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2) (adenomatous polyposis coli)
• Alternative to gene target
  adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233

Gene info

• Identity
  HGNC:7572
• Gene
  MYH2
• Long gene name
  myosin heavy chain 2
• Synonyms gene
  • IBM3
• Synonyms gene name
  • myosin, heavy polypeptide 2, skeletal muscle, adult
  • inclusion body myopathy 3, autosomal dominant
• Synonyms
  • MYH2A
  • MYHSA2
  • MyHC-IIa
  • MYHas8
  • MyHC-2A
• Locus
  17p13.1
• Discovery year
  2001-06-22
• Entrez gene record
  4620
• Pubmed identfication
  • 7545970
  • 11889243
• RefSeq identity
  • NM_017534
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000130363

Gene info

• Identity
  HGNC:173
• Gene
  ACVR2A
• Long gene name
  activin A receptor type 2A
• Synonyms gene
  • ACVR2
• Synonyms gene name
  • activin A receptor, type II
  • activin A receptor, type IIA
• Synonyms
  • ACTRII
• Locus
  2q22.3-q23.1
• Discovery year
  1993-09-17
• Entrez gene record
  92
• Pubmed identfication
  • 1314589
  • 10702675
• RefSeq identity
  • NM_001616
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000150603

Gene info

• Identity
  HGNC:174
• Gene
  ACVR2B
• Long gene name
  activin A receptor type 2B
• Synonyms gene name
  • activin A receptor, type IIB
• Synonyms
  • ActR-IIB
• GenBank acession
  • X77533
• Locus
  3p22.2
• Discovery year
  1997-03-19
• Entrez gene record
  93
• Pubmed identfication
  • 8161782
  • 9621519
• RefSeq identity
  • NM_001106
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000131291

Gene info

• Identity
  HGNC:583
• Gene
  APC
• Long gene name
  APC regulator of WNT signaling pathway
• Synonyms gene name
  • adenomatosis polyposis coli
  • adenomatous polyposis coli
  • APC, WNT signaling pathway regulator
• Synonyms
  • DP2
  • DP3
  • DP2.5
  • PPP1R46
• Synonyms name
  • protein phosphatase 1, regulatory subunit 46
• GenBank acession
  • M74088
• Locus
  5q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  324
• Pubmed identfication
  • 1651563
• RefSeq identity
  • NM_000038
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000128806
• Locus Specific Databases
  • Adenomatous polyposis coli mutation database
  • UMD Locus Specific Databases
  • Global Variome shared LOVD
  • APC database at LOVD-China
  • LOVD - Leiden Open Variation Database
  • LRG_130

Gene info

• Identity
  HGNC:7670
• Gene
  NCOA3
• Long gene name
  nuclear receptor coactivator 3
• Synonyms
  • RAC3
  • AIB1
  • ACTR
  • p/CIP
  • TRAM-1
  • CAGH16
  • TNRC16
  • KAT13B
  • bHLHe42
  • SRC-3
  • SRC3
• Synonyms name
  • receptor-associated coactivator 3
  • thyroid hormone receptor activator molecule 1
• GenBank acession
  • AF012108
• Locus
  20q13.12
• Discovery year
  1999-12-17
• Entrez gene record
  8202
• Pubmed identfication
  • 9252329
  • 9346901
• RefSeq identity
  • NM_006534
• Classification
  • Basic helix-loop-helix proteins
  • Lysine acetyltransferases
• VEGA ID
  OTTHUMG00000033061

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