anti-human IL-4 mAb IL4-II, biotinylated

• Catalog number
  3410-6-1000
• Price
  Please ask
• Size
  1 mg

• Categories
  Antibodies
• Description
  This monoclonal antibody enables sensitive and specific detection of human IL-4 in immunoassays such as ELISA and ELISpot.
• Recommandation
  We recommend IL4-II as detection antibody in ELISA and ELISpot in combination with capture antibody IL4-I.
• Antibody Clone
  IL4-II
• Enzyme Conjugate
  biotin
• Format
  biotinylated
• Application
  ELISpot, ELISA
• Reactivities
  human, non-human primates
• Analytes
  IL4
• Specificity
  Native and recombinant IL-4
• Contents
  IL4-II, biotinylated, supplied at 1 mg/ml in PBS with 0.02% sodium azide
• Datasheet
• Product Header
  Monoclonal antibody specific for IL-4
• GeneID
  The monoclonal antibody cross-reacts with IL-4 from non-human primates.
• Shelf Life
  18 months
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  Mabtech supplies antibodies that are for research of human proteins.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  Interleukin 4 (IL4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It is used for dendritic and T cell therapy. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell. It is closely related and has functions similar to Interleukin 13. Recombinant, GMP rec. E. coli interleukin-4 for cell culture supplied by GENTAUR. Free samples on request.

• Gene target
  IL-4   mAb   IL4-II   biotinylated  
• Gene symbol
  IL4, SNORD114-4, STAT6, IL36G, IL25, IL10RB, IL22, IL18, IL37, IL6R
• Short name
  anti- IL-4 mAb IL4-II, biotinylated
• Technique
  anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans
• Alternative name
  Antibody tohuman Interleukin-4 monoclonal interleukin 4-II, biotinylated
• Alternative technique
  antibodies
• Alternative to gene target
  interleukin 4, BCGF-1 and BCGF1 and BSF-1 and BSF1 and IL-4, IL4 and IDBG-42701 and ENSG00000113520 and 3565, growth factor activity, Extracellular, Il4 and IDBG-172024 and ENSMUSG00000000869 and 16189, IL4 and IDBG-644671 and ENSBTAG00000015957 and 280824

Gene info

• Identity
  HGNC:6014
• Gene
  IL4
• Long gene name
  interleukin 4
• Synonyms
  • BSF1
  • IL-4
  • BCGF1
  • BCGF-1
  • MGC79402
• Synonyms name
  • B_cell stimulatory factor 1
  • lymphocyte stimulatory factor 1
  • B cell growth factor 1
• GenBank acession
  • M23442
• Locus
  5q31.1
• Discovery year
  1988-08-10
• Entrez gene record
  3565
• Pubmed identfication
  • 3016727
• RefSeq identity
  • NM_000589
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000059724

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:11368
• Gene
  STAT6
• Long gene name
  signal transducer and activator of transcription 6
• Synonyms gene name
  • signal transducer and activator of transcription 6, interleukin-4 induced
• Synonyms
  • D12S1644
  • IL-4-STAT
• GenBank acession
  • BC005823
  • BQ028928
• Locus
  12q13.3
• Discovery year
  1995-11-09
• Entrez gene record
  6778
• Pubmed identfication
  • 9605853
  • 8085155
• RefSeq identity
  • NM_003153
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000171194
• Locus Specific Databases
  • LRG_1369

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:5965
• Gene
  IL10RB
• Long gene name
  interleukin 10 receptor subunit beta
• Synonyms gene
  • CRFB4
  • D21S58
  • D21S66
• Synonyms gene name
  • interleukin 10 receptor, beta
• Synonyms
  • CRF2-4
  • CDW210B
  • IL-10R2
• GenBank acession
  • U08988
• Locus
  21q22.11
• Discovery year
  1993-04-06
• Entrez gene record
  3588
• Pubmed identfication
  • 8314576
  • 9312047
• Classification
  • Interleukin receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000065128
• Locus Specific Databases
  • LRG_152

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

Gene info

• Identity
  HGNC:5986
• Gene
  IL18
• Long gene name
  interleukin 18
• Synonyms gene name
  • interleukin 18 (interferon-gamma-inducing factor)
• Synonyms
  • IGIF
  • IL1F4
  • IL-1g
  • IL-18
• Synonyms name
  • interferon-gamma-inducing factor
• GenBank acession
  • U90434
• Locus
  11q23.1
• Discovery year
  1997-07-25
• Entrez gene record
  3606
• Pubmed identfication
  • 7477296
  • 9693051
• RefSeq identity
  • NM_001562
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000167006

Gene info

• Identity
  HGNC:15563
• Gene
  IL37
• Long gene name
  interleukin 37
• Synonyms gene
  • IL1F7
• Synonyms gene name
  • interleukin 1 family, member 7 (zeta)
• Synonyms
  • FIL1
  • FIL1Z
  • FIL1(ZETA)
  • IL-1H4
  • IL-1RP1
  • IL-1F7
• Synonyms name
  • interleukin 1, zeta
  • interleukin-1 homolog 4
  • interleukin-1-related protein
• GenBank acession
  • AF201832
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27178
• Pubmed identfication
  • 10625660
  • 10512743
  • 12496389
• RefSeq identity
  • NM_014439
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131345

Gene info

• Identity
  HGNC:6019
• Gene
  IL6R
• Long gene name
  interleukin 6 receptor
• Synonyms
  • CD126
  • IL-6R
  • IL-1Ra
  • IL6RA
  • gp80
• Synonyms name
  • membrane glycoprotein 80
  • interleukin 6 receptor subunit alpha
• GenBank acession
  • X12830
• Locus
  1q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  3570
• Pubmed identfication
  • 8428753
  • 12633863
• RefSeq identity
  • NM_000565
• Classification
  • CD molecules
  • Interleukin receptors
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000036073

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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