Integrin alpha 3 Antibody

• Catalog number
  PA1621-1
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Integrin alpha 3
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  mouse, rat
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha 3(1026-1040aa ALYEAKRQKAEMKSQ), identical to the related mouse and rat sequences.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Integrin alpha 3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Integrin alpha 3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.
• Related articles
  1. Akula, S. M., Pramod, N. P., Wang, F.-Z., Chandran, B. Integrin alpha-3/beta-1 (CD 49c/29) is a cellular receptor for Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) entry into the target cells. Cell 108: 407-419, 2002. 2. Dulabon, L., Olson, E. C., Taglienti, M. G., Eisenhuth, S., McGrath, B., Walsh, C. A., Kreidberg, J. A., Anton, E. S. Reelin binds alpha-3-beta-1 integrin and inhibits neuronal migration. Neuron 27: 33-44, 2000. 3. Takada Y, Murphy E, Pil P, Chen C, Ginsberg MH, Hemler ME (Oct 1991). "Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen".
• Gene Name
  ITGA3
• Protein Name
  Integrin alpha-3
• Gene Full Name
  integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor)
• Synonyms
  AA407068 antibody|Antigen identified by monoclonal antibody J143 antibody|CD49 antigen like family member C antibody|CD49 antigen-like family member C antibody|CD49c antibody|CD49c antigen antibody|FLJ34631 antibody|FLJ34704 antibody|FRP 2 antibody|FRP-2 antibody|FRP2 antibody|galactoprotein B3 antibody|GAP B3 antibody|GAPB3 antibody|Integrin alpha 3 antibody|Integrin alpha-3 light chain antibody|Integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody|ITA3_HUMAN antibody|ITGA 3 antibody|ITGA3 antibody|MSK18 antibody|URO1 antibody|VCA 2 antibody|VCA2 antibody|Very late activation protein 3 receptor alpha 3 subunit antibody|Very Late Activation Protein 3 Receptor Alpha 3 Subunit antibody|VL3A antibody|VLA 3 alpha chain antibody|VLA 3 subunit alpha antibody|VLA-3 subunit alpha antibody|VLA3 antibody|VLA3a antibody
• Uniprot ID
  P26006
• Description
  The Integrin alpha 3 Antibody is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Integrin   alpha  
• Gene symbol
  ITGAM, ITGAX, ITGA3
• Short name
  Integrin alpha 3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Integrin a 3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6149
• Gene
  ITGAM
• Long gene name
  integrin subunit alpha M
• Synonyms gene
  • CR3A
  • CD11B
• Synonyms gene name
  • integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
  • integrin, alpha M (complement component 3 receptor 3 subunit)
• Synonyms
  • MAC-1
  • CD11b
• Synonyms name
  • complement component 3 receptor 3 subunit
  • macrophage-1 antigen alpha subunit
• GenBank acession
  • J03925
• Locus
  16p11.2
• Discovery year
  1988-08-05
• Entrez gene record
  3684
• RefSeq identity
  • NM_000632
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000176612
• Locus Specific Databases
  • LRG_1333

Gene info

• Identity
  HGNC:6152
• Gene
  ITGAX
• Long gene name
  integrin subunit alpha X
• Synonyms gene
  • CD11C
• Synonyms gene name
  • integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
  • integrin, alpha X (complement component 3 receptor 4 subunit)
• Synonyms
  • CD11c
• Synonyms name
  • complement component 3 receptor 4 subunit
• GenBank acession
  • BC038237
• Locus
  16p11.2
• Discovery year
  1988-08-15
• Entrez gene record
  3687
• Pubmed identfication
  • 3284962
  • 2303426
• RefSeq identity
  • NM_000887
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000132465

Gene info

• Identity
  HGNC:6139
• Gene
  ITGA3
• Long gene name
  integrin subunit alpha 3
• Synonyms gene
  • MSK18
• Synonyms gene name
  • antigen identified by monoclonal antibody J143
  • integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
• Synonyms
  • CD49c
  • VLA3a
  • VCA-2
  • GAP-B3
• Synonyms name
  • alpha 3 subunit of VLA-3 receptor
  • antigen CD49C
• GenBank acession
  • M59911
• Locus
  17q21.33
• Discovery year
  1992-02-27
• Entrez gene record
  3675
• Pubmed identfication
  • 1655803
  • 9704023
• RefSeq identity
  • NM_005501
• Classification
  • Integrin alpha subunits
  • CD molecules
• VEGA ID
  OTTHUMG00000161890

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products