Integrin alpha 7 Antibody

• Catalog number
  bs-1816R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Integrin alpha 7 Primary Polyclonal Antibody
• Also known as
  Integrin alpha 7 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Integrin alpha 7/ITGA7
• Specificity
  This is a highly specific antibody against Integrin alpha 7/ITGA7.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  730-780/1181
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin alpha 7
• Gene ID number
  3679
• Swiss Prot
  Q13683
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Integrin alpha-7; ITGA7; UNQ46/PRO768
• Description
  The Anti-Integrin alpha 7/ITGA7 is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Integrin   alpha  
• Gene symbol
  ITGA7
• Short name
  Anti-Integrin alpha 7/ITGA7
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Integrin alpha 7 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6143
• Gene
  ITGA7
• Long gene name
  integrin subunit alpha 7
• Synonyms gene name
  • integrin, alpha 7
• Locus
  12q13.2
• Discovery year
  1992-02-27
• Entrez gene record
  3679
• Pubmed identfication
  • 7607681
• RefSeq identity
  • NM_002206
• Classification
  • Integrin alpha subunits
• VEGA ID
  OTTHUMG00000170699
• Locus Specific Databases
  • LRG_871

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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