RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody, Cy5 Conjugated

• Catalog number
  bs-6581R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RNA polymerase II CTD repeat YSPTSPS phospho Ser2
• Specificity
  This is a highly specific antibody against RNA polymerase II CTD repeat YSPTSPS phospho Ser2.
• Modification
  Phosphorylation
• Modification site
  Ser2
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  1600-1630/1970
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human RNA polymerase II RPB1 around Ser2
• Gene ID number
  6193
• Swiss Prot
  P46782
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicate and transcriptase for the viral RNA circular genome.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  S5; 40S ribosomal protein S5; RPS5
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  RNA   polymerase   CTD   repeat   YSPTSPS   Ser2   Conjugated  
• Gene symbol
  LINC02488, LINC00973, LINC01929, LINC02489, LINC02560, LINC02582, ZKSCAN2-DT, SCAT1, EGFLAM-AS1
• Short name
  Anti-RNA polymerase II CTD repeat YSPTSPS phospho Ser2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates, RNAs are to store at -70 C
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-RNA polymerase II CTD repeat YSPTSPS phospho Ser2 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:53467
• Gene
  LINC02488
• Long gene name
  long intergenic non-protein coding RNA 2488
• Synonyms
  • CTD-2316B1
• GenBank acession
  • DR033777
  • AI929023
• Locus
  5q14.3
• Discovery year
  2017-04-27
• Pubmed identfication
  • 28415557
• Classification
  • Long intergenic non-protein coding RNAs

Gene info

• Identity
  HGNC:48868
• Gene
  LINC00973
• Long gene name
  long intergenic non-protein coding RNA 973
• Synonyms
  • CTD-2021J15.2
• Locus
  3q12.1
• Discovery year
  2013-06-19
• Entrez gene record
  100506377
• Pubmed identfication
  • 28796819
  • 29870803
• Classification
  • Long intergenic non-protein coding RNAs
• VEGA ID
  OTTHUMG00000159060

Gene info

• Identity
  HGNC:52751
• Gene
  LINC01929
• Long gene name
  long intergenic non-protein coding RNA 1929
• Synonyms
  • CTD-2171N6.1
• Locus
  18q21.2
• Discovery year
  2016-12-07
• Entrez gene record
  101927229
• Pubmed identfication
  • 28618399
• RefSeq identity
  • NR_110743
• Classification
  • Long intergenic non-protein coding RNAs
• VEGA ID
  OTTHUMG00000176191

Gene info

• Identity
  HGNC:53470
• Gene
  LINC02489
• Long gene name
  long intergenic non-protein coding RNA 2489
• Synonyms
  • CTD-2589M5.4
• Locus
  11p11.2
• Discovery year
  2017-04-27
• Entrez gene record
  101928919
• Pubmed identfication
  • 28415557
• Classification
  • Long intergenic non-protein coding RNAs

Gene info

• Identity
  HGNC:53600
• Gene
  LINC02560
• Long gene name
  long intergenic non-protein coding RNA 2560
• Synonyms
  • CTD-2619J13.13
• Locus
  19q13.43
• Discovery year
  2017-06-16
• Pubmed identfication
  • 28611953
• Classification
  • Long intergenic non-protein coding RNAs

Gene info

• Identity
  HGNC:53792
• Gene
  LINC02582
• Long gene name
  long intergenic non-protein coding RNA 2582
• Synonyms
  • CTD-2354A18.1
• Locus
  18q22.3
• Discovery year
  2017-12-20
• Entrez gene record
  100505817
• Pubmed identfication
  • 29254165
• RefSeq identity
  • NR_038340
• Classification
  • Long intergenic non-protein coding RNAs

Gene info

• Identity
  HGNC:53912
• Gene
  ZKSCAN2-DT
• Long gene name
  ZKSCAN2 divergent transcript
• Synonyms
  • CTD-2547G23.4
• Locus
  16p12.1
• Discovery year
  2018-05-24
• Pubmed identfication
  • 29780284
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:52930
• Gene
  SCAT1
• Long gene name
  S-phase cancer associated transcript 1
• Synonyms gene
  • LINC02081
• Synonyms gene name
  • long intergenic non-protein coding RNA 2081
• Synonyms
  • CTD-2357A8.3
  • XLOC_012582
• Locus
  17q25.3
• Discovery year
  2016-12-20
• Entrez gene record
  101928710
• Pubmed identfication
  • 28028307
  • 28125665
  • 29491376
• RefSeq identity
  • NR_110848
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000177747

Gene info

• Identity
  HGNC:41169
• Gene
  EGFLAM-AS1
• Long gene name
  EGFLAM antisense RNA 1
• Synonyms gene name
  • EGFLAM antisense RNA 1 (non-protein coding)
• Synonyms
  • lncRNA-LOWEG
  • CTD-2108O9.1
• Synonyms name
  • lncRNA low expressed in gastric cancer
• Locus
  5p13.1
• Discovery year
  2011-05-24
• Pubmed identfication
  • 26537802
  • 29603493
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162101

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products