IL-23 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-1193R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  IL-23 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-IL-23 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  IL-23
• Specificity
  This is a highly specific antibody against IL-23.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-23
• Gene ID Number
  51561
• Swiss Prot
  Q9NPF7
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  P19; SGRF; IL-23; IL-23A; IL23P19; Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19; IL23A; UNQ2498/PRO5798
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-IL-23 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  IL-23  
• Gene symbol
  IL23A, IL22, IGHV3-23, IGKV2D-23, SNORD116-23, SNORD115-23, SNORD114-23, IGKV2-23, ERVW-23, IGLV2-23
• Short name
  Anti-IL-23
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  IL-23 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15488
• Gene
  IL23A
• Long gene name
  interleukin 23 subunit alpha
• Synonyms gene name
  • interleukin 23, alpha subunit p19
• Synonyms
  • SGRF
  • IL23P19
  • IL-23
  • IL-23A
  • P19
• Synonyms name
  • interleukin-six, G-CSF related factor
• GenBank acession
  • AB030000
• Locus
  12q13.3
• Discovery year
  2001-04-10
• Entrez gene record
  51561
• Pubmed identfication
  • 11114383
• RefSeq identity
  • NM_016584
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000187402

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

Gene info

• Identity
  HGNC:5588
• Gene
  IGHV3-23
• Long gene name
  immunoglobulin heavy variable 3-23
• GenBank acession
  • M99660
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28442
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152091

Gene info

• Identity
  HGNC:5796
• Gene
  IGKV2D-23
• Long gene name
  immunoglobulin kappa variable 2D-23 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2D-23
  • immunoglobulin kappa variable 2D-23 pseudogene
• GenBank acession
  • X71887
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28886
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151605

Gene info

• Identity
  HGNC:33089
• Gene
  SNORD116-23
• Long gene name
  small nucleolar RNA, C/D box 116-23
• Synonyms
  • HBII-85-23
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033434
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003337
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33042
• Gene
  SNORD115-23
• Long gene name
  small nucleolar RNA, C/D box 115-23
• Synonyms
  • HBII-52-23
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033800
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003315.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33011
• Gene
  SNORD114-23
• Long gene name
  small nucleolar RNA, C/D box 114-23
• Synonyms
  • 14q(II-23)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767603
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003216.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5780
• Gene
  IGKV2-23
• Long gene name
  immunoglobulin kappa variable 2-23 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2-23
  • immunoglobulin kappa variable 2-23 pseudogene
• GenBank acession
  • X71885
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28924
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151638

Gene info

• Identity
  HGNC:49311
• Gene
  ERVW-23
• Long gene name
  endogenous retrovirus group W member 23
• Synonyms gene name
  • endogenous retrovirus group W, member 23
• GenBank acession
  • HG421062
• Locus
  12p13.31
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:5890
• Gene
  IGLV2-23
• Long gene name
  immunoglobulin lambda variable 2-23
• GenBank acession
  • X14616
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28813
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151234

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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