BACE2 Antibody , ALEXA FLUOR 488

• Catalog number
  bs-10494R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  BACE2 Polyclonal Antibody , ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-BACE2 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BACE2
• Specificity
  This is a highly specific antibody against BACE2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  345-375/518
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BACE2
• Gene ID Number
  25825
• Swiss Prot
  Q9Y5Z0
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Asp 1; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Down region aspartic protease; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; BACE2; UNQ418/PRO852
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-BACE2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  BACE2  
• Gene symbol
  BACE2-IT1, BACE2
• Short name
  Anti-BACE2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  BACE2 Polyclonal Antibody , ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16024
• Gene
  BACE2-IT1
• Long gene name
  BACE2 intronic transcript 1
• Synonyms gene
  • C21orf75
  • NCRNA00228
• Synonyms gene name
  • chromosome 21 open reading frame 75
  • non-protein coding RNA 228
  • BACE2 intronic transcript 1 (non-protein coding)
• Synonyms
  • PRED43
• Locus
  21q22.2
• Discovery year
  2002-11-26
• Entrez gene record
  282569
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000086745

Gene info

• Identity
  HGNC:934
• Gene
  BACE2
• Long gene name
  beta-secretase 2
• Synonyms gene
  • AEPLC
• Synonyms gene name
  • beta-site APP-cleaving enzyme 2
• Synonyms
  • CEAP1
  • DRAP
  • ALP56
• Synonyms name
  • memapsin 1
• GenBank acession
  • AF117892
• Locus
  21q22.2-q22.3
• Discovery year
  2000-05-23
• Entrez gene record
  25825
• Pubmed identfication
  • 10965118
  • 10830953
• Classification
  • Peptidase family A1
• VEGA ID
  OTTHUMG00000086742

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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