Hemocyanin-Keyhole Limpet (KLH), Native
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Catalog number
6288-25
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Price
Please ask
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Size
25 mg
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Synonyms
KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin
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Alternative_names
KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin
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Description
Pure KLH ideal for antibody purification and as a carrier protein and immunogen
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Recombinant
No
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Source
Megathura crenulata, Giant keyhole limpet
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Purity by SDS PAGE
≥ 95%
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Assay
MPLC-SEC
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Molecular Weight
370 kDa (One major band)
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Storage Temp
2-8°C
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Shipping
Gel pack
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Shelf Life
36 months
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Concentration
25 mg/vial
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Appearance
Liquid
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Physical form description
25 mg in opalescent blue liquid which may contain some particulate and fibers.
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Background Information
Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been in use as an immunological reagent for many years. It is used as a carrier protein for antibody production against antigens. Recent advances in immunology and the role immune system plays in diseases have opened a whole new era of product development activities aimed at developing novel therapeutics for teaching the body's immune system to fight diseases. The approach involves the use of highly immunogenic molecule like the hemocyanin for non-specific immunostimulation (NSI) or active specific immunostimulation (ASI) using conjugate vaccines, wherein the tumor (disease) specific antigens are covalently bound to carrier protein like KLH and the product used in human clinical studies. BioVision’s native KLH has low endotoxin content and consistent high concentration in a phosphate buffer containing no extraneous metal ions for product stabilization, however with improved stability. This research grade material is suited for use in vaccine product development activities and also for routine immunological studies, antibody production, production of activated KLH and other developmental activities.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Gene target
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Short name
Hemocyanin-Keyhole Limpet (KLH), Native
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Alternative name
Hemocyanin-Keyhole Limpet (KLH), Native
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