Anti- Nuclear Factor Kappa B (NFkB) Antibody
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Catalog numberGEN2007076
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PricePlease ask
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Size100ug
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Long nameBiotin-Linked Antibody to Nuclear Factor Kappa B (NFkB)
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AntigenNuclear Factor Kappa B (NFkB)
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Synonim namesN/A
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Other namesnuclear factor kappa B; nuclear factor kappa B; N/A
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Gene nameNuclear Factor Kappa B (NFkB) ; NFkB
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Gene synonimsNfkb; N/A
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CategoryAntibodies
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ClonalityPolyclonal Antibodies
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CloneNot applicable to Polyclonal Antibodies
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Reacts withDue to limitted amount of tested species we cannot guarantee that no crossreactivity will occur.
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SpecificityThe antibody is a rabbit polyclonal antibody raised against NFkB conjugated to biotin. It has been selected for its ability to recognize NFkB in immunohistochemical staining andwestern blotting. ;This is an antibody designed to detect Nuclear Factor Kappa B (NFkB) ; NFkB
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Purification methodThis antibody was purified via Affinity Chromatography
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Form AppearanceSupplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
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Concentration0.2mg/ml
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Storage shipping and handlingThe antibody is shipped at +4 degrees Celsius. Upon receving, freeze at -20. For longer periods of time we recommend keeping the vial frozen at -40 or -80. Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody. Due to transportation or handling reasons, small amounts of the antibody might get caught on the lid or walls of the vial. We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom.
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ApplicationsImmunohistochemistry (IHC), ELISA, EIA, IFA, ELI-Spot, Western Blot (WB)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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PropertiesIf you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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French translationanticorps
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Gene target
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Gene symbolNFKBIE, NFKBIB, NFKB1
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Short nameAnti-Nuclear Factor Kappa B (NFkB)
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameNuclear Factor Kappa B (NFkB) Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameNFKB inhibitor epsilon
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Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-07-01
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Entrez gene record
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Pubmed identfication
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Classification
- Ankyrin repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNFKB inhibitor beta
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Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-07-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ankyrin repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear factor kappa B subunit 1
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Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-11-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NF-kappa B complex subunits
- Ankyrin repeat domain containing
- IPT domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data