NFkBIa (Nuclear Factor kappa B Inhibitor alpha, IkappaB alpha, I(Kappa)B(alpha), IKB alpha, IKBA, MAD-3, Major Histocompatibility Complex Enhancer Binding Protein MAD3, NFkB Inhibitor alpha, Nuclear Factor of kappa Light Chain Gene Enhancer in B cells, Nu Antibody

  • Catalog number
    GEN601498
  • Price
    Please ask
  • Size
    100ul
  • Also known as
    NFkBIa
  • Other names
    NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; ikB-alpha; IkappaBalpha; I-kappa-B-alpha; OTTHUMP00000178842; nuclear factor of kappa light chain gene enhancer in B-cells; major histocompatibility complex enhancer-binding protein MAD3; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    NFKBIA; NFKBIA; IKBA; MAD-3; NFKBI; IKBA; MAD3; NFKBI
  • Gene name synonims
    NFKBIA; NFKBIA; IKBA; MAD-3; NFKBI; IKBA; MAD3; NFKBI
  • Other gene names
    NFKBIA; NFKBIA; IKBA; MAD-3; NFKBI; IKBA; MAD3; NFKBI
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG
  • Clone
    6k217
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes human IkappaB-alpha; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Supernatant
  • Form Appearance
    Supplied as a liquid.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
  • Tested applications
    Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • Description
    The NFkBIa ( Factor kappa B Inhibitor alpha, IkappaB alpha, I(Kappa)B(alpha), IKB alpha, IKBA, MAD-3, Major Histocompatibility Complex Enhancer Binding Protein MAD3, NFkB Inhibitor alpha, Factor of kappa Light Chain Enhancer in B cells, Nu Antibody is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene
    NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
  • French translation
    anticorps
  • Gene target
    NFkBIa   Factor   kappa   Inhibitor   alpha   IkappaB   alpha   Kappa   alpha   IKB   alpha   IKBA   MAD-3   Major   Histocompatibility   Complex   Enhancer   Binding   Protein   MAD3   NFkB   Inhibitor   alpha   Factor   kappa   Light   Chain   Gene   Enhancer   cells  
  • Gene symbol
    MXD3, NFKBIA, AMPD1, MXD1, MIR1302-3, MIR509-3, MIR7-3, PIRC14, PIRC12
  • Short name
    NFkBIa ( Factor kappa B Inhibitor alpha, IkappaB alpha, I(Kappa)B(alpha), IKB alpha, IKBA, MAD-3, Major Histocompatibility Complex Enhancer Binding Protein MAD3, NFkB Inhibitor alpha, Factor of kappa Light Chain Enhancer in B cells, Nu Antibody
  • Technique
    Antibody, light, antibodies against human proteins, antibodies for
  • Alternative name
    Anti-NFkBIa (Nuclear Factor kappa B Inhibitor alpha, IkappaB alpha, I(Kappa)B(alpha), IKB alpha, IKBA, MAD-3, Major Histocompatibility Complex Enhancer Binding Protein MAD3, NFkB Inhibitor alpha, Nuclear Factor of kappa Light Chain Gene Enhancer in B cells, Nu
  • Alternative technique
    antibodies
  • Alternative to gene target
    nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, IKBA and MAD-3 and NFKBI, NFKBIA and IDBG-4758 and ENSG00000100906 and 4792, NF-kappaB binding, nuclei, Nfkbia and IDBG-140708 and ENSMUSG00000021025 and 18035, BIKBA and IDBG-632547 and ENSBTAG00000016683 and 282291
  • Tissue
    cells
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:37518
  • Gene
    PIRC14
  • Long gene name
    piwi-interacting RNA cluster 14
  • Locus
    3
  • Discovery year
    2009-11-05
  • Entrez gene record
    100313784
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
  • Identity
    HGNC:37516
  • Gene
    PIRC12
  • Long gene name
    piwi-interacting RNA cluster 12
  • Locus
    3
  • Discovery year
    2009-11-05
  • Entrez gene record
    100313808
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
MeSH Data
  • Name
    Blotting, Western
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Filters
NFkBIa Factor kappa B Inhibitor alpha IkappaB alpha I Kappa
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