BML-278

• Catalog number
  2379-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
• Description
  Cell-permeable. A structurally novel activator of SIRT1 (EC₅₀ = 1 µM). Displays selectivity over SIRT2 and 3 (EC₅₀ = 25 and 50 µM respectively).
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₅NO₄
• Molecular Weight
  391.46
• Cell Permeable
  Yes
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (~ 5 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  A SIRT1 activator
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  O=C(OCC)C1=CN(CC2=CC=CC=C2)C=C(C(OCC)=O)C1C3=CC=CC=C3
• InChi
  InChI=1S/C24H25NO4/c1-3-28-23(26)20-16-25(15-18-11-7-5-8-12-18)17-21(24(27)29-4-2)22(20)19-13-9-6-10-14-19/h5-14,16-17,22H,3-4,15H2,1-2H3
• InChi Key
  JOHFECBOWRGWJZ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BML-278  
• Gene symbol
  FLNB
• Short name
  BML-278
• Alternative name
  BML-278

Gene info

• Identity
  HGNC:3755
• Gene
  FLNB
• Long gene name
  filamin B
• Synonyms gene
  • FLN1L
  • LRS1
• Synonyms gene name
  • filamin B, beta (actin binding protein 278)
  • Larsen syndrome 1 (autosomal dominant)
  • filamin B, beta
• Synonyms
  • TAP
  • TABP
  • ABP-278
  • FH1
• Synonyms name
  • actin binding protein 278
  • beta filamin
• GenBank acession
  • AF043045
• Locus
  3p14.3
• Discovery year
  1997-06-20
• Entrez gene record
  2317
• Pubmed identfication
  • 8327473
  • 10449914
  • 14991055
  • 16801345
• RefSeq identity
  • NM_001457
• Classification
  • Filamins
• VEGA ID
  OTTHUMG00000159158

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