Bml 277 ,CHK2 kinase inhibitor
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Catalog number
SIH-436-50MG
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Price
Please ask
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Size
50 mg
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Research Area s
Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
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Category
Small Molecules
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Product Type
Inhibitor
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CAS No
516480-79-8
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MolecularFormula
C20H14ClN3O2
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Molecular Weight
363.8
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Purity
≥98% (TLC)
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Solubility
Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml)
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Appearance
Off-white solid
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Storage Temperature
-20°C
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Shipping Temperature
Shipped Ambient
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbol
CHEK2
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Short name
Bml 277 ,CHK2 kinase inhibitor
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Alternative name
Bml 277 ,CHK2 phosphorylation catalyst suppressor
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Gene info
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Identity
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Gene
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Long gene name
checkpoint kinase 2
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Synonyms gene
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Synonyms gene name
- CHK2 (checkpoint, S.pombe) homolog
- CHK2 checkpoint homolog (S. pombe)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-09-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
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