CD130 (CDw130, gp130, GP130-RAPS, IL-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, IL 6 Signal Transducer, IL6ST, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)
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Catalog numberGEN608958
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PricePlease ask
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Size100ug
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Also known asCD130
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Other namesN/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesN/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneB-T2
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human CD130, soluble and membrane bound gp130 receptor. This antibody has been reported to block the activity of IL-6.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodPurified
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Form AppearanceSupplied as a liquid in PBS, 0.09% sodium azide.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsELISA (EL/EIA), Flow Cytometry (FC/FACS)
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DescriptionThe CD130 (CDw130, gp130, GP130-RAPS, IL-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, IL 6 Signal Transducer, IL6ST, Glycoprotein 130, Oncostatin-M Receptor Subunit alpha) is a α- or alpha protein sometimes glycoprotein present in blood. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolIL6R, IL6ST, IL6, IL36G, IL25, IL22, IL18, IL37, IL17C, IL17A
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Short nameCD130 (CDw130, gp130, GP130-RAPS, IL-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, IL 6 Signal Transducer, IL6ST, Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)
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Alternative nameAnti-CD130 (CDw130, gp130, GP130-RAPS, Interleukin-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, Interleukin 6 Signal Transducer, IL6ST, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)
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Alternative to gene targetinterleukin 6 signal transducer (gp130, oncostatin M receptor), CD130 and CDW130 and GP130 and IL-6RB, IL6ST and IDBG-21516 and ENSG00000134352 and 3572, interleukin-27 receptor activity, Extracellular, Il6st and IDBG-182517 and ENSMUSG00000021756 and 16195, BT.66498 and IDBG-629050 and ENSBTAG00000017745 and 522155
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 6 receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 6 cytokine family signal transducer
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Synonyms gene name
- interleukin 6 signal transducer (gp130, oncostatin M receptor)
- interleukin 6 signal transducer
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-08-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibronectin type III domain containing
- CD molecules
- Interleukin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 6
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Synonyms gene
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Synonyms gene name
- interleukin 6 (interferon, beta 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
- Interferons
- Interleukin 6 type cytokine family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 25
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Synonyms gene
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Synonyms gene name
- interleukin 17E
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-01-26
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Pubmed identfication
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameinterleukin 18
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Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 37
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 7 (zeta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 17C
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Synonyms
-
GenBank acession
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Locus
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Discovery year2000-01-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 17A
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Synonyms gene
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Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-10-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases