CD130 (CDw130, gp130, GP130-RAPS, Interleukin-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, Interleukin 6 Signal Transducer, IL6ST, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)

  • Catalog number
    MBS608958
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [CD130]
  • Products_name_syn
    [Anti -CD130 (CDw130, gp130, GP130-RAPS, Interleukin-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, Interleukin 6 Signal Transducer, IL6ST, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)]
  • Clonality
    Monoclonal
  • Clone
    [B-T2]
  • Reactivity
    Human
  • Specificity
    Recognizes human CD130, soluble and membrane bound gp130 receptor. This antibody has been reported to block the activity of IL-6.
  • Purity
    Purified Purified
  • Form
    Supplied as a liquid in PBS, 0.09% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    ELISA (EL/EIA), Flow Cytometry (FC/FACS)
  • Description
    The CD130 (CDw130, gp130, GP130-RAPS, Interleukin-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, Interleukin 6 Signal Transducer, IL6ST, Glycoprotein 130, Oncostatin-M Receptor Subunit alpha) is a α- or alpha protein sometimes glycoprotein present in blood. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    CD130   CDw130   gp130   GP130-RAPS   Interleukin-6   Receptor   Subunit   beta   IL-6   Receptor   Subunit   beta   IL-6R   Subunit   beta   IL6R-beta   IL-6R-beta   IL-6RB   Interleukin   Signal   Transducer   IL6ST   Membrane   Glycoprotein   130   Oncostatin-M   Receptor   Subunit   alpha  
  • Gene symbol
    IL6R, IL6ST, IL6R-AS1, IL36G, IL25, IL22, IL18, IL37, IL6, IL17C
  • Short name
    CD130 (CDw130, gp130, GP130-RAPS, Interleukin-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, Interleukin 6 Signal Transducer, IL6ST, Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)
  • Host
    Mouse
  • Isotype
    IgG1
  • Alternative name
    CD130 (CDw130, gp130, GP130-RAPS, Interleukin-6 Receptor functionnal sequence b, Interleukin-6 Receptor functionnal sequence b, Interleukin-6R functionnal sequence b, interleukin 6 receptor-b, Interleukin-6R-b, Interleukin-6RB, Interleukin 6 Signal Transducer, interleukin 6 signal transducer (gp130, oncostatin M receptor), Membrane Glycoprotein 130, Oncostatin-M Receptor functionnal sequence a)
  • Alternative to gene target
    interleukin 6 signal transducer (gp130, oncostatin M receptor), CD130 and CDW130 and GP130 and IL-6RB, IL6ST and IDBG-21516 and ENSG00000134352 and 3572, interleukin-27 receptor activity, Extracellular, Il6st and IDBG-182517 and ENSMUSG00000021756 and 16195, BT.66498 and IDBG-629050 and ENSBTAG00000017745 and 522155
Gene info
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CD130 CDw130 gp130 GP130 RAPS Interleukin 6 Receptor Subunit
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