IL-21, human recombinant

• Catalog number
  4182-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Za11, IL-21.
• Alternative_names
  Za11, IL-21, Interleukin-21
• Description
  A cytokine regulating cells of the immune system
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Purity
  ≥90%
• Biological activity
  The recombinant human IL-21 is fully biologically active when compared to standard. The ED₅₀ as determined by the dose-dependent stimulation of human peripheral blood mononuclear cells is
• Molecular Weight
  15.5 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized (from 1 mg/ml solution containing no additives).
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 µg/µl (Note: Gently pippetting to dissolve). The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
• Background Information
  Recombinant human IL-21 is a homodimeric, non-glycosylated polypeptide containing 133 amino acid residues and has a molecular weight of 15.5 kDa.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-21  
• Gene symbol
  IL21, IL17C, IL22, IL21-AS1, PIRC105, HTOR, SNORD115-21, SNORD114-21
• Short name
  IL-21, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Interleukin-21, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6005
• Gene
  IL21
• Long gene name
  interleukin 21
• Synonyms
  • Za11
  • IL-21
• GenBank acession
  • AF254069
• Locus
  4q27
• Discovery year
  2000-03-29
• Entrez gene record
  59067
• Pubmed identfication
  • 11081504
  • 17947662
• RefSeq identity
  • NM_021803
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000133073
• Locus Specific Databases
  • LRG_1263

Gene info

• Identity
  HGNC:5983
• Gene
  IL17C
• Long gene name
  interleukin 17C
• Synonyms
  • IL-17C
  • CX2
  • IL-21
  • MGC126884
  • MGC138401
• GenBank acession
  • AF152099
• Locus
  16q24.2
• Discovery year
  2000-01-20
• Entrez gene record
  27189
• Pubmed identfication
  • 10639155
• RefSeq identity
  • NM_013278
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000173241

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

Gene info

• Identity
  HGNC:40299
• Gene
  IL21-AS1
• Long gene name
  IL21 antisense RNA 1
• Synonyms gene name
  • IL21 antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC045668
• Locus
  4q27
• Discovery year
  2012-08-09
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000150127

Gene info

• Identity
  HGNC:37609
• Gene
  PIRC105
• Long gene name
  piwi-interacting RNA cluster 105
• Locus
  21
• Discovery year
  2009-11-05
• Entrez gene record
  100313936
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:5285
• Gene
  HTOR
• Long gene name
  5-hydroxytryptamine (serotonin) oxygenase regulator
• Locus
  21
• Discovery year
  2001-06-22
• Entrez gene record
  3349
• Pubmed identfication
  • 93675

Gene info

• Identity
  HGNC:33040
• Gene
  SNORD115-21
• Long gene name
  small nucleolar RNA, C/D box 115-21
• Synonyms
  • HBII-52-21
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033603
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003313.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33009
• Gene
  SNORD114-21
• Long gene name
  small nucleolar RNA, C/D box 114-21
• Synonyms
  • 14q(II-21)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767599
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003214.1
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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